Alkenes as Chelating Groups in Diastereoselective Additions of Organometallics to Ketones
نویسندگان
چکیده
Alkenes have been discovered to be chelating groups to Zn(II), enforcing highly stereoselective additions of organozincs to β,γ-unsaturated ketones. 1H NMR studies and DFT calculations provide support for this surprising chelation mode. The results expand the range of coordinating groups for chelation-controlled carbonyl additions from heteroatom Lewis bases to simple C-C double bonds, broadening the 60 year old paradigm.
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عنوان ژورنال:
دوره 33 شماره
صفحات -
تاریخ انتشار 2014